Recombinant antigens expressed in Pichia pastoris for the diagnosis of sleeping sickness caused by Trypanosoma brucei gambiense.

Screening tests for gambiense sleeping sickness, such as the CATT/T. b. gambiense and a recently developed lateral flow tests, are hitherto based on native variant surface glycoproteins (VSGs), namely LiTat 1.3 and LiTat 1.5, purified from highly virulent trypanosome strains grown in rodents.We have...

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Autores principales:	Stijn Rogé, Liesbeth Van Nieuwenhove, Magali Meul, Annick Heykers, Annette Brouwer de Koning, Nicolas Bebronne, Yves Guisez, Philippe Büscher
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	Public Library of Science (PLoS) 2014-07-01
Colección:	PLoS Neglected Tropical Diseases
Acceso en línea:	http://europepmc.org/articles/PMC4102443?pdf=render
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