In Vivo Determinants of Hepatitis C Virus Adaptation and Escape From Neutralizing Antibody AR5ASummaryWhat You Need to Know

Background & Aims: Mechanisms of hepatitis C virus (HCV) adaptation and escape from broadly neutralizing antibodies (bNAbs) have been primarily studied in vitro. Here, we used a previously developed in vivo adapted J6/JFH1A876P virus and the highly bNAb sensitive hypervariable region 1 (HVR1) de...

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Principais autores:	Rodrigo Velázquez-Moctezuma, Rani Burm, Lieven Verhoye, Laura Collignon, Kenn Holmbeck, Erick Giang, Mansun Law, Jens Bukh, Philip Meuleman, Jannick Prentoe
Formato:	Artigo
Idioma:	Inglês
Publicado:	Elsevier 2026-01-01
Series:	Cellular and Molecular Gastroenterology and Hepatology
Assuntos:	Antibody Escape AR5A Hepatitis C Virus Human-liver Chimeric Mice In Vivo Adaptation
Acceso en liña:	http://www.sciencedirect.com/science/article/pii/S2352345X25002255
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