A novel peptide MIB1-223aa encoded by exosomal circMIB1 from cancer-associated fibroblasts drives triple-negative breast cancer metastasis and stemness via stabilizing MIB1 to activate Notch signaling

Introduction: Emerging evidence has indicated that the complex interactions between tumor microenvironment (TME) and cancer cells play a pivotal role in driving tumor initiation and metastasis. Cancer associated fibroblasts (CAFs), major cell components in the TME, exert significant effects on malig...

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Главные авторы:	Fangzhou Ye, Yiran Liang, Jianing Wang, Jiayin Song, Yuhan Jin, Lei Wang, Dan Luo, Xiaoyan Li, Yaming Li, Dianwen Han, Tong Chen, Bing Chen, Wenjing Zhao, Lijuan Wang, Qifeng Yang
Формат:	Artigo
Язык:	Inglês
Опубликовано:	Elsevier 2026-03-01
Серии:	Journal of Advanced Research
Предметы:	Triple negative breast cancer Cancer associated fibroblasts Exosome Protein-coding ability circMIB1
Online-ссылка:	http://www.sciencedirect.com/science/article/pii/S2090123225004333
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