The HNF1α-regulated lncRNA HNF1A-AS1 reverses the malignancy of hepatocellular carcinoma by enhancing the phosphatase activity of SHP-1

Abstract Background Our previous study has demonstrated that hepatocyte nuclear factor 1α (HNF1α) exerts potent therapeutic effects on hepatocellular carcinoma (HCC). However, the molecular mechanisms by which HNF1α reverses HCC malignancy need to be further elucidated. Methods lncRNA microarray was...

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Bibliografische Detailangaben

Hauptverfasser:	Chen-Hong Ding, Chuan Yin, Shi-Jie Chen, Liang-Zhi Wen, Kai Ding, Shu-Juan Lei, Jin-Pei Liu, Jian Wang, Kai-xian Chen, Hua-liang Jiang, Xin Zhang, Cheng Luo, Wei-Fen Xie
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	BMC 2018-02-01
Schriftenreihe:	Molecular Cancer
Schlagworte:	HNF1α HNF1A-AS1 Hepatocellular carcinoma, SHP-1, phosphatase activity
Online-Zugang:	http://link.springer.com/article/10.1186/s12943-018-0813-1
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