Hypoxia-responsive COF nanomedicine co-delivers gambogic acid and BODIPY for synergistic lung cancer PDT suppression

The hypoxic tumor microenvironment (TME) in lung cancer contributes significantly to therapeutic resistance. To address this, we developed a hypoxia-responsive nanomedicine, BG@COF-AZO, using an azobenzene-functionalized covalent organic framework (COF) for the co-delivery of gambogic acid (GA) and...

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Podrobná bibliografie

Hlavní autoři:	Ruoyu Wang, Ling Xiao, Beibei Hong, Jiahui Wang, Hegen Li, Lei Zhou, Zhanxia Zhang
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Elsevier 2025-10-01
Edice:	Materials & Design
Témata:	Hypoxia-responsive nanomedicine Covalent organic framework Lung cancer Gambogic acid Photodynamic therapy
On-line přístup:	http://www.sciencedirect.com/science/article/pii/S0264127525011293
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