Fasudil inhibits α-synuclein aggregation through ROCK-inhibition-mediated mechanisms
ROCK inhibitors such as fasudil protected against dopaminergic degeneration and other neurodegenerative processes in several experimental models through inhibition of neuroinflammation and activation of survival signaling pathways, and clinical trials have been initiated. More recently, fasudil has...
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| Principais autores: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Elsevier
2025-03-01
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| coleção: | Neurotherapeutics |
| Assuntos: | |
| Acesso em linha: | http://www.sciencedirect.com/science/article/pii/S1878747925000224 |
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