Chronic glucocorticoid exposure disrupts lactate homeostasis and hippocampal neurogenesis by reducing cerebrovascular monocarboxylate transporter 1, leading to behavioral abnormalities in mice
Prolonged glucocorticoid elevation is strongly associated with brain dysfunction and the pathogenesis of stress-related disorders, including several psychiatric disorders. Elevated lactate levels have been reported in the brains of patients with psychiatric disorders and animal models of chronic str...
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| Auteurs principaux: | , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Elsevier
2026-09-01
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| Collection: | Journal of Pharmacological Sciences |
| Sujets: | |
| Accès en ligne: | http://www.sciencedirect.com/science/article/pii/S1347861326000393 |
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