Efficacy and safety of human soluble thrombomodulin (ART-123) for treatment of patients in France with sepsis-associated coagulopathy: post hoc analysis of SCARLET

Abstract Background The phase 3 multinational SCARLET study evaluated the efficacy and safety of a recombinant human soluble thrombomodulin (ART-123) for treatment of sepsis-associated coagulopathy (SAC), which correlates with increased mortality risk in patients with sepsis. Although no significant...

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Bibliografische Detailangaben

Hauptverfasser:	Bruno François, Maud Fiancette, Julie Helms, Emmanuelle Mercier, Jean-Baptiste Lascarrou, Toshihiko Kayanoki, Kosuke Tanaka, David Fineberg, Jean-Louis Vincent, Xavier Wittebole
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Elsevier 2021-03-01
Schriftenreihe:	Annals of Intensive Care
Schlagworte:	Sepsis Sepsis-associated coagulopathy Thrombomodulin ART-123 Heparin France
Online-Zugang:	https://doi.org/10.1186/s13613-021-00842-4
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