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In Vivo Iterative Adjuvant Screening Identifies an Intranasal Vaccine Formulation for Elicitation of Protective Mucosal Immune Responses Against SARS-CoV-2

<b>Background:</b> Intranasal (I.N.) vaccination holds promise to elicit mucosal immunity that counters respiratory pathogens at the site of infection. For subunit protein vaccines, immunostimulatory adjuvants are typically required. <b>Methods:</b> We screened a panel of 22 lipid-phase adjuvants to...

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Bibliografski detalji
Glavni autori: Yang Jiao, Sara H. Mahmoud, Chengjin Ye, Yuan Luo, Wei-Chiao Huang, Qinzhe Li, Shiqi Zhou, Yiting Song, Moriya Tsuji, Luis Martinez-Sobrido, Jonathan F. Lovell
Format: Artigo
Jezik:Inglês
Izdano: MDPI AG 2025-11-01
Serija:Pharmaceutics
Teme:
Online pristup:https://www.mdpi.com/1999-4923/17/11/1422
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