PIWI associated siRNAs and piRNAs specifically require the Caenorhabditis elegans HEN1 ortholog henn-1.

Small RNAs--including piRNAs, miRNAs, and endogenous siRNAs--bind Argonaute proteins to form RNA silencing complexes that target coding genes, transposons, and aberrant RNAs. To assess the requirements for endogenous siRNA formation and activity in Caenorhabditis elegans, we developed a GFP-based se...

Ausführliche Beschreibung

Bibliografische Detailangaben

Hauptverfasser:	Taiowa A Montgomery, Young-Soo Rim, Chi Zhang, Robert H Dowen, Carolyn M Phillips, Sylvia E J Fischer, Gary Ruvkun
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Public Library of Science (PLoS) 2012-01-01
Schriftenreihe:	PLoS Genetics
Online-Zugang:	https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22536158/?tool=EBI
Tags:	Tag hinzufügen Keine Tags, Fügen Sie das erste Tag hinzu!