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EPIC: Inferring relevant cell types for complex traits by integrating genome-wide association studies and single-cell RNA sequencing.

More than a decade of genome-wide association studies (GWASs) have identified genetic risk variants that are significantly associated with complex traits. Emerging evidence suggests that the function of trait-associated variants likely acts in a tissue- or cell-type-specific fashion. Yet, it remains...

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Bibliografiske detaljer
Principais autores: Rujin Wang, Dan-Yu Lin, Yuchao Jiang
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science (PLoS) 2022-06-01
Serier:PLoS Genetics
Online adgang:https://doi.org/10.1371/journal.pgen.1010251
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