Insulators to Improve the Safety of Retroviral Vectors for HIV Gene Therapy
Retroviral vector gene therapy is a promising approach to treating HIV-1. However, integrated vectors are mutagens with the potential to dysregulate nearby genes and cause severe adverse side effects. Leukemia has already been a documented severe adverse event in gene therapy clinical trials for the...
Gorde:
| Egile Nagusiak: | , |
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| Formatua: | Artigo |
| Hizkuntza: | Inglês |
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MDPI AG
2016-02-01
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| Saila: | Biomedicines |
| Gaiak: | |
| Sarrera elektronikoa: | http://www.mdpi.com/2227-9059/4/1/4 |
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