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Correlations Between Methionine Cycle Metabolism, COMT Genotype, and Polyneuropathy in L-Dopa Treated Parkinson’s Disease: A Preliminary Cross-Sectional Study

Background: Polyneuropathy (pnp) is recognized as a clinical feature of Parkinson’s disease (PD). Whether pnp is a result of the alpha-synucleinopathy or related to treatment is debated. Previous studies support underlying disturbances in the methionine cycle mediated by L-dopa. Objective: Describe...

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Hauptverfasser: Mattias Andréasson, Lovisa Brodin, José Miguel Laffita-Mesa, Per Svenningsson
Format: Artigo
Sprache:Inglês
Veröffentlicht: SAGE Publishing 2017-11-01
Schriftenreihe:Journal of Parkinson’s Disease
Online-Zugang:https://doi.org/10.3233/JPD-171127
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