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Study protocol for a multicenter, multinational prospective randomized controlled trial comparing outcomes in subjects with Gram-negative bacteremia who have blood culture evaluation using Fast Antibiotic Susceptibility Testing vs. standard of care testing: the FAST trial

Abstract Background Novel, rapid blood culture diagnostics can provide faster antibiotic susceptibility results (AST) compared to standard methods but their impact on clinical outcomes is unclear and not assessed in many prospective clinical trials. Methods This study is a two-arm, multicenter, mult...

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Principais autores: Ritu Banerjee, Lauren Komarow, Yixuan Li, Qihang Wu, Lucia Sanchez-Gonzalez, Donald Mau, Erin Abbenante, Nyssa Schwager, Andrew Dodd, Maria Souli, Holly S. Geres, Sarah Doernberg, Kerryl Greenwood-Quaintance, Scott R. Evans, Henry F. Chambers, Vance G. Fowler, Robin Patel, Antibacterial Resistance Leadership Group
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2025-11-01
Serier:Trials
Fag:
Bloodstream infection
Antibiotic susceptibility testing
Gram-negative
Bacteremia
Online adgang:https://doi.org/10.1186/s13063-025-09228-4
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