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Defunctionalizing intracellular organelles such as mitochondria and peroxisomes with engineered phospholipase A/acyltransferases

Approaches for manipulating individual organelles are important for learning more about their functions. Here the authors report a tool utilising phospholipase A/acyltransferases (PLAATs) for rapid defunctionalisation of organelles through remodelling of the membrane phospholipids.

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Detalhes bibliográficos
Principais autores: Satoshi Watanabe, Yuta Nihongaki, Kie Itoh, Toru Uyama, Satoshi Toda, Shigeki Watanabe, Takanari Inoue
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Portfolio 2022-07-01
coleção:Nature Communications
Acesso em linha:https://doi.org/10.1038/s41467-022-31946-5
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