HIV acquisition is associated with increased antimicrobial peptides and reduced HIV neutralizing IgA in the foreskin prepuce of uncircumcised men.

<h4>Background</h4>The foreskin is the site of most HIV acquisition in uncircumcised heterosexual men. Although HIV-exposed, seronegative (HESN) uncircumcised men demonstrate HIV-neutralizing IgA and increased antimicrobial peptides (AMPs) in the foreskin prepuce, no prospective studies have examine...

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Principais autores:	Taha Hirbod, Xiangrong Kong, Godgrey Kigozi, Anthony Ndyanabo, David Serwadda, Jessica L Prodger, Aaron A Tobian, Fred Nalugoda, Maria J Wawer, Kamnoosh Shahabi, Olga L Rojas, Jennifer L Gommerman, Kristina Broliden, Rupert Kaul, Ronald H Gray
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Public Library of Science (PLoS) 2014-10-01
Colecção:	PLoS Pathogens
Acesso em linha:	https://doi.org/10.1371/journal.ppat.1004416
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