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Modulation of EGFR Gene Transcription by a Polymorphic Repetitive Sequence – a Link between Genetics and Epigenetics

The epidermal growth factor receptor (EGFR) plays a crucial role in growth, differentiation and motility of normal as well as tumor cells. The transduction of extracellular signals to the cytoplasm via the receptor not only depends on ligand binding, but is also determined by the receptor density on...

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Principais autores: F. Gebhardt, H. BÜrger, B. Brandt
Format: Artigo
Jezik:Inglês
Izdano: SAGE Publishing 2000-01-01
Serija:The International Journal of Biological Markers
Online dostop:https://doi.org/10.1177/172460080001500120
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