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Aging Triggers H3K27 Trimethylation Hoarding in the Chromatin of <i>Nothobranchius furzeri</i> Skeletal Muscle

Aging associates with progressive loss of skeletal muscle function, sometimes leading to sarcopenia, a process characterized by impaired mobility and weakening of muscle strength. Since aging associates with profound epigenetic changes, epigenetic landscape alteration analysis in the skeletal muscle...

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Main Authors: Chiara Cencioni, Johanna Heid, Anna Krepelova, Seyed Mohammad Mahdi Rasa, Carsten Kuenne, Stefan Guenther, Mario Baumgart, Alessandro Cellerino, Francesco Neri, Francesco Spallotta, Carlo Gaetano
Format: Artigo
Language:Inglês
Published: MDPI AG 2019-09-01
Series:Cells
Subjects:
aging
skeletal muscle
sarcopenia
frailty
chromatin
epigenetic changes
histone modifications
<i>nothobranchius furzeri</i>
Online Access:https://www.mdpi.com/2073-4409/8/10/1169
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