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Antiglycative Activity and RAGE Expression in Rett Syndrome

Rett syndrome (RTT) is a human neurodevelopmental disorder, whose pathogenesis has been linked to both oxidative stress and subclinical inflammatory status (OxInflammation). Methylglyoxal (MG), a glycolytic by-product with cytotoxic and pro-oxidant power, is the major precursor in vivo of advanced g...

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Principais autores: Valeria Cordone, Alessandra Pecorelli, Mascia Benedusi, Silvano Santini, Stefano Falone, Joussef Hayek, Fernanda Amicarelli, Giuseppe Valacchi
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2019-02-01
Serier:Cells
Fag:
methylglyoxal
glyoxalases
advanced glycation end products
MeCP2
dicarbonyl stress
fibroblasts
Online adgang:https://www.mdpi.com/2073-4409/8/2/161
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