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The RNA binding protein RBMS3 inhibits the metastasis of breast cancer by regulating Twist1 expression

Abstract Background Metastasis remains the biggest obstacle for breast cancer treatment. Therefore, identification of specific biomarker of metastasis is very necessary. The RNA binding protein 3 (RBMS3) acts as a tumor suppressor in various cancers. Whereas, its role and underlying molecular mechan...

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Principais autores: Lei Zhu, Pei-Wen Xi, Xiao-Xia Li, Xi Sun, Wen-Bin Zhou, Tian-Song Xia, Liang Shi, Yue Hu, Qiang Ding, Ji-Fu Wei
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2019-02-01
coleção:Journal of Experimental & Clinical Cancer Research
Assuntos:
Breast cancer
RBMS3
Twist1
MMP2
Metastasis
mRNA stability
Acesso em linha:http://link.springer.com/article/10.1186/s13046-019-1111-5
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