RASIP1-positive TECs in pancreatic adenocarcinoma: a potential novel type of endothelial cells correlated with “hot” tumors

Abstract Pancreatic adenocarcinoma (PDAC) is a highly lethal malignancy characterized by profound resistance to immunotherapy. Converting immunologically “cold” tumors into “hot” tumors by enhancing T cell infiltration represents a promising therapeutic strategy, yet the vascular mechanisms regulati...

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Principais autores:	Shubin Zhang, Yujian He, He Chang, Yuyao Tian, Xin Wang, Zhijie Feng, Wei Qi, Jianhua Liu
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Nature Portfolio 2026-03-01
coleção:	Scientific Reports
Assuntos:	Pancreatic adenocarcinoma RASIP1 Tumor endothelial cells T cells infiltration
Acesso em linha:	https://doi.org/10.1038/s41598-026-40948-y
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