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Epigenome-wide analysis of sperm cells identifies IL22 as a possible germ line risk locus for psoriatic arthritis.

Psoriasis and its associated inflammatory arthritis, psoriatic arthritis (PsA), have a clear heritable component, but a large proportion of the heritable risk remains unexplained by gene sequence variation. This study aimed to determine if epigenetic factors contribute to the missing heritability in...

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Библиографические подробности
Главные авторы: Remy A Pollock, Laila Zaman, Vinod Chandran, Dafna D Gladman
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science (PLoS) 2019-01-01
Серии:PLoS ONE
Online-ссылка:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0212043&type=printable
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