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Cross-species functional genomic analysis identifies resistance genes of the histone deacetylase inhibitor valproic acid.

The mechanisms of successful epigenetic reprogramming in cancer are not well characterized as they involve coordinated removal of repressive marks and deposition of activating marks by a large number of histone and DNA modification enzymes. Here, we have used a cross-species functional genomic appro...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Rakel Brendsdal Forthun, Tanima Sengupta, Hanne Kim Skjeldam, Jessica Margareta Lindvall, Emmet McCormack, Bjørn Tore Gjertsen, Hilde Nilsen
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Public Library of Science (PLoS) 2012-01-01
Sarja:PLoS ONE
Linkit:http://europepmc.org/articles/PMC3498369?pdf=render
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