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Development and validation of a reversed-phase HPLC-UV method for simultaneous determination of levosulpiride and omeprazole in human plasma: Applicability of the method for evaluation of pharmacokinetic drug-drug interactions.

Levosulpiride and omeprazole are co-prescribed for gastrointestinal disorders associated with depression and anxiety. Objective of the study was to develop a sensitive, robust and simple method for simultaneous analysis of levosulpiride and omeprazole in human plasma and applicability of the method...

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Hlavní autoři: Muhammad Hashim, Lateef Ahmad, Amjad Khan, Muhammad Faheem
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science (PLoS) 2024-01-01
Edice:PLoS ONE
On-line přístup:https://doi.org/10.1371/journal.pone.0309453
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