Neutrophil Influx and Chemokine Production during the Early Phases of the Antitumor Response to the Vascular Disrupting Agent DMXAA (ASA404)

5,6-Dimethylxanthenone-4-acetic acid (DMXAA) acts through tumor vascular disruption and cytokine production and is the first of its class to enter phase 3 trials. We characterized leukocytes and cytokines in murine Colon 38 tumors before and after DMXAA treatment. Tumor mass declined 50% 24 hours af...

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Autors principals:	Liang-Chuan S. Wang, Lotte Thomsen, Rachel Sutherland, Charu B. Reddy, Sofian M. Tijono, Chun-Jen J. Chen, Catherine E. Angel, P. Rod Dunbar, Lai-Ming Ching
Format:	Artigo
Idioma:	Inglês
Publicat:	Elsevier 2009-08-01
Col·lecció:	Neoplasia: An International Journal for Oncology Research
Accés en línia:	http://www.sciencedirect.com/science/article/pii/S1476558609801358
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