Reduction of leucocyte cell surface disulfide bonds during immune activation is dynamic as revealed by a quantitative proteomics workflow (SH-IQ)

Communication through cell surface receptors is crucial for maintaining immune homeostasis, coordinating the immune response and pathogen clearance. This is dependent on the interaction of cell surface receptors with their ligands and requires functionally active conformational states. Thus, immune...

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Detalles Bibliográficos

Autores principales:	Monika Stegmann, A. Neil Barclay, Clive Metcalfe
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	The Royal Society 2018-09-01
Colección:	Open Biology
Materias:	allosteric disulfide bonds redox regulation thioredoxin proteomics immune regulation immune receptors
Acceso en línea:	https://royalsocietypublishing.org/doi/pdf/10.1098/rsob.180079
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