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Suberoylanilide Hydroxamic Acid (SAHA) Treatment Reveals Crosstalk Among Proteome, Phosphoproteome, and Acetylome in Nasopharyngeal Carcinoma Cells

Suberoylanilide hydroxamic acid (SAHA), a famous histone deacetylase (HDAC) inhibitor, has been utilized in clinical treatment for cutaneous T-cell lymphoma. Previously, the mechanisms underlying SAHA anti-tumor activity mainly focused on acetylome. However, the characteristics of SAHA in terms of o...

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書誌詳細
主要な著者: Huichao Huang, Ying Fu, Yankun Duan, Ye Zhang, Miaolong Lu, Zhuchu Chen, Maoyu Li, Yongheng Chen
フォーマット: Artigo
言語:Inglês
出版事項: Frontiers Media S.A. 2022-05-01
シリーズ:Frontiers in Genetics
主題:
オンライン・アクセス:https://www.frontiersin.org/articles/10.3389/fgene.2022.873840/full
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