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Fabrication and sustained-release characterization of a TRPC3-inhibitor-loaded electrospun PVA nanofiber scaffold

PurposeElectrospun nanofiber scaffolds are an appealing platform for localized small-molecule delivery, but burst release from hydrophilic polymers such as polyvinyl alcohol (PVA) limits their utility for sustained pharmacologic exposure. In this proof-of-concept study, we developed and characterize...

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Principais autores: Gemma Toogood, Liping Zhang, Dejian Ma, Vijay Boda, Wei Li, Robin Evans, Junwang Xu
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2026-06-01
coleção:Frontiers in Materials
Assuntos:
crosslinking
diabetic wound-healing
drug delivery
electrospinning
nanofiber scaffold
polyvinyl alcohol
Acesso em linha:https://www.frontiersin.org/articles/10.3389/fmats.2026.1828526/full
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