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Loss of ZNF451 mediates fibroblast activation and promotes lung fibrosis

Abstract Background No effective therapies for pulmonary fibrosis (PF) exist because of the unclear molecular pathogenesis and the lack of effective therapeutic targets. Zinc finger protein 451 (ZNF451), a transcriptional regulator, plays crucial roles in the pathogenesis of several diseases. Howeve...

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主要な著者: Hong Peng, Yu Zhang, Jiali Min, Yuexin Tan, Shanshan Liu
フォーマット: Artigo
言語:Inglês
出版事項: BMC 2024-04-01
シリーズ:Respiratory Research
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オンライン・アクセス:https://doi.org/10.1186/s12931-024-02781-7
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