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The role of s-palmitoylation in neurological diseases: implication for zDHHC family

S-palmitoylation is a reversible posttranslational modification, and the palmitoylation reaction in human-derived cells is mediated by the zDHHC family, which is composed of S-acyltransferase enzymes that possess the DHHC (Asp-His-His-Cys) structural domain. zDHHC proteins form an autoacylation inte...

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Bibliografische Detailangaben
Hauptverfasser: Dan Liao, Yutao Huang, Dan Liu, Haofuzi Zhang, Xinyu Shi, Xin Li, Peng Luo
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2024-01-01
Schriftenreihe:Frontiers in Pharmacology
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Online-Zugang:https://www.frontiersin.org/articles/10.3389/fphar.2023.1342830/full
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