Exosome and BCR-ABL mediated molecular alterations in endothelial cells in chronic myeloid leukemia: identification of seven genes and their regulatory network

Background Chronic myeloid leukemia (CML) progression relies on dynamic crosstalk between leukemic cells and vascular niches. Here, we investigate how exosomes and BCR/ABL overexpression influence endothelial functions, aiming to identify key mediators of leukemia-induced microenvironmental remodeli...

ver descrição completa

Detalhes bibliográficos

Principais autores:	Zhenglei Shen, Honghua Cao, Yeying Zhou, Wenwen Mao, Kunmei Liu, Jingying Zhu, Ming He, Yunru Mao, Ni Luo, Lei Feng, Heng Le, Liying Song, HuaXian Li, Yasar Mehmood Yousafzai, Asad Zia, Xuezhong Gu, Shiwen Zhang
Formato:	Artigo
Idioma:	Inglês
Publicado em:	PeerJ Inc. 2025-12-01
coleção:	PeerJ
Assuntos:	Chronic myeloid leukemia (CML) Human umbilical vein endothelial cells(HUVECs) K562 cell line Exosomes Biomarkers
Acesso em linha:	https://peerj.com/articles/20371.pdf
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!