TRIM15 Mediates ubiquitination of Paxillin to facilitate the progression of ovarian cancer

Abstract Background Globally, among gynecological malignancies, ovarian cancer (OC) stands as an important factor contributing to mortality. E3 ubiquitin ligase activity is a common characteristic found in the tripartite motif (TRIM) proteins, contributing significantly to post-translational modific...

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Hlavní autoři:	Jiaqi Xu, Tiantian Wu, Fei Wu, Yue Zhu, Meng Liu, Yan Zhang, Wenxin Gao, Weifeng Qian, Guannan Feng, Xiaoyan Huang, Xiaoxue Xi, Shunyu Hou
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	BMC 2026-05-01
Edice:	Cancer Cell International
Témata:	TRIM15 Ovarian cancer Paxillin Ubiquitination Phosphorylation FAK
On-line přístup:	https://doi.org/10.1186/s12935-026-04260-z
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