Synthesis and Preclinical Evaluation of Two Novel ⁶⁸Ga-Labeled Bispecific PSMA/FAP-Targeted Tracers with 2-Nal-Containing PSMA-Targeted Pharmacophore and Pyridine-Based FAP-Targeted Pharmacophore

Some bispecific radiotracers have been developed to overcome the limitations of monospecific tracers and improve detection sensitivity for heterogeneous tumor lesions. Here, we aim to synthesize two bispecific tracers targeting prostate-specific membrane antigen (PSMA) and fibroblast activation prot...

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Bibliografische Detailangaben

Hauptverfasser:	Arsyangela Verena, Helen Merkens, Chao-Cheng Chen, Devon E. Chapple, Lei Wang, Shreya Bendre, Antonio A. W. L. Wong, François Bénard, Kuo-Shyan Lin
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	MDPI AG 2024-02-01
Schriftenreihe:	Molecules
Schlagworte:	bispecific radiotracers PSMA FAP PET/CT gallium-68 prostate cancer
Online-Zugang:	https://www.mdpi.com/1420-3049/29/4/800
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