Metabolic Remodeling, Inflammasome Activation, and Pyroptosis in Macrophages Stimulated by Porphyromonas gingivalis and Its Outer Membrane Vesicles

Porphyromonas gingivalis is one of the bacterial species most closely associated with periodontitis and can shed large numbers of outer membrane vesicles (OMVs), which are increasingly thought to play a significant role in bacterial virulence and pathogenicity. Macrophages are amongst the first immu...

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Autores principales:	Andrew J. Fleetwood, Man K.S. Lee, William Singleton, Adrian Achuthan, Ming-Chin Lee, Neil M. O'Brien-Simpson, Andrew D. Cook, Andrew J. Murphy, Stuart G. Dashper, Eric C. Reynolds, John A. Hamilton
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	Frontiers Media S.A. 2017-08-01
Colección:	Frontiers in Cellular and Infection Microbiology
Materias:	macrophages metabolism inflammasome P. gingivalis vesicles pyroptosis
Acceso en línea:	http://journal.frontiersin.org/article/10.3389/fcimb.2017.00351/full
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