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TREM2 dependent and independent functions of microglia in Alzheimer’s disease

Abstract Microglia are central players in brain innate immunity and have been the subject of extensive research in Alzheimer’s disease (AD). In this review, we aim to summarize the genetic and functional discoveries that have advanced our understanding of microglia reactivity to AD pathology. Given...

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Détails bibliographiques
Auteurs principaux: Jinchao Hou, Yun Chen, Gary Grajales-Reyes, Marco Colonna
Format: Artigo
Langue:Inglês
Publié: BMC 2022-12-01
Collection:Molecular Neurodegeneration
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Accès en ligne:https://doi.org/10.1186/s13024-022-00588-y
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