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Some mice lacking intrinsic, as well as death receptor induced apoptosis and necroptosis, can survive to adulthood

Programmed cell death, in particular the intrinsic apoptotic pathway, has been shown to play a critical role in the shaping of tissues during embryonic development. The multi-BCL-2 Homology (BH) domain effectors of apoptosis, BAX, BAK, and BOK, are essential for cell killing in the intrinsic apoptot...

Ausführliche Beschreibung

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Bibliografische Detailangaben
Hauptverfasser: Francine F. S. Ke, Kerstin Brinkmann, Anne K. Voss, Andreas Strasser
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2022-04-01
Schriftenreihe:Cell Death and Disease
Online-Zugang:https://doi.org/10.1038/s41419-022-04731-x
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