Passive Transfer of Immune Sera Induced by a Zika Virus-Like Particle Vaccine Protects AG129 Mice Against Lethal Zika Virus Challenge

Zika virus (ZIKV) poses a serious public health threat due to its association with birth defects in developing fetuses and Guillain-Barré Syndrome in adults. We are developing a ZIKV vaccine based on virus-like particles (VLPs) generated in transiently transfected HEK293 cells. The genetic construct...

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Bibliographic Details

Main Authors:	Diego Espinosa, Jason Mendy, Darly Manayani, Lo Vang, Chunling Wang, Tiffany Richard, Ben Guenther, Jayavani Aruri, Jenny Avanzini, Fermin Garduno, Peggy Farness, Marc Gurwith, Jon Smith, Eva Harris, Jeff Alexander
Format:	Artigo
Language:	Inglês
Published:	Elsevier 2018-01-01
Series:	EBioMedicine
Subjects:	Zika virus Virus-like particle vaccine Correlates of protection Passive transfer Vaccine development
Online Access:	http://www.sciencedirect.com/science/article/pii/S2352396417304917
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