High Prevalence and Clinical Relevance of Genes Affected by Chromosomal Breaks in Colorectal Cancer.

<h4>Background</h4>Cancer is caused by somatic DNA alterations such as gene point mutations, DNA copy number aberrations (CNA) and structural variants (SVs). Genome-wide analyses of SVs in large sample series with well-documented clinical information are still scarce. Consequently, the impact of SVs...

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Bibliografiska uppgifter

Huvudupphov:	Evert van den Broek, Maurits J J Dijkstra, Oscar Krijgsman, Daoud Sie, Josien C Haan, Joleen J H Traets, Mark A van de Wiel, Iris D Nagtegaal, Cornelis J A Punt, Beatriz Carvalho, Bauke Ylstra, Sanne Abeln, Gerrit A Meijer, Remond J A Fijneman
Materialtyp:	Artigo
Språk:	Inglês
Utgiven:	Public Library of Science (PLoS) 2015-01-01
Serie:	PLoS ONE
Länkar:	https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0138141&type=printable
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