Effects of the Thyroid Endocrine System on Gonadal Sex Ratios and Sex-Related Gene Expression in the Pufferfish Takifugu rubripes

To examine the effect and mechanism of thyroid hormone on gonadal sex differentiation, Takifugu rubripes larvae were treated with goitrogen (methimazole, MET, 1000 μg/g), and thyroxine (T4, 2nM) from 25 to 80 days after hatching (dah). Gonadal histology and sex ratios of fish were then determined at...

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Detalhes bibliográficos

Principais autores:	Zhen Yuan, Xufang Shen, Hongwei Yan, Jieming Jiang, Binwei Liu, Lei Zhang, Yumeng Wu, Ying Liu, Qi Liu
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2021-05-01
coleção:	Frontiers in Endocrinology
Assuntos:	Takifugu rubripes methimazole thyroid hormone sex differentiation RNA-seq
Acesso em linha:	https://www.frontiersin.org/articles/10.3389/fendo.2021.674954/full
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