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Tiamulin-Resistant Mutants of the Thermophilic Bacterium <i>Thermus thermophilus</i>

Tiamulin is a semisynthetic pleuromutilin antibiotic that binds to the 50S ribosomal subunit A site and whose (((2-diethylamino)ethyl)thio)-acetic acid tail extends into the P site to interfere with peptide bond formation. We have isolated spontaneous tiamulin-resistant mutants of the thermophilic b...

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Detalles Bibliográficos
Principais autores: Erin E. Killeavy, Gerwald Jogl, Steven T. Gregory
Formato: Artigo
Idioma:Inglês
Publicado: MDPI AG 2020-06-01
Series:Antibiotics
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Acceso en liña:https://www.mdpi.com/2079-6382/9/6/313
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