Heat-killed Prevotella intermedia promotes the progression of oral squamous cell carcinoma by inhibiting the expression of tumor suppressors and affecting the tumor microenvironment

Abstract Background Oral microbial dysbiosis contributes to the development of oral squamous cell carcinoma (OSCC). Our previous study showed that Prevotella intermedia (P. intermedia) were enriched in the oral mucosal surface, plaque, and saliva of patients with OSCC. Intratumoral microbiome could...

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Bibliografische Detailangaben

Hauptverfasser:	Yifan Zhou, Yao Qin, Jingjing Ma, Zhiyuan Li, Weiwei Heng, Lei Zhang, Hong Liu, Ruowei Li, Miaomiao Zhang, Qiao Peng, Pei Ye, Ning Duan, Ting Liu, Wenmei Wang, Xiang Wang
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	BMC 2024-03-01
Schriftenreihe:	Experimental Hematology & Oncology
Schlagworte:	Oral squamous cell carcinoma Prevotella intermedia IL-17 signal pathway GABAergic system Tumor suppressor genes
Online-Zugang:	https://doi.org/10.1186/s40164-024-00500-y
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