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In Situ Remodeling of Efferocytosis via Lesion‐Localized Microspheres to Reverse Cartilage Senescence

Abstract Efferocytosis, an intrinsic regulatory mechanism to eliminate apoptotic cells, will be suppressed due to the delayed apoptosis process in aging‐related diseases, such as osteoarthritis (OA). In this study, cartilage lesion‐localized hydrogel microspheres are developed to remodel the in situ...

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Principais autores: Wei Xiong, Zeyu Han, Sheng‐Long Ding, Haoran Wang, Yawei Du, Wenguo Cui, Ming‐Zhu Zhang
Format: Artigo
Sprog:Inglês
Udgivet: Wiley 2024-05-01
Serier:Advanced Science
Fag:
cartilage senescence
efferocytosis
Hydrogel microspheres
lesion‐localized
osteoarthritis
Online adgang:https://doi.org/10.1002/advs.202400345
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