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IgG Fc engineering to modulate antibody effector functions

ABSTRACT Therapeutic monoclonal antibodies are among the most effective biotherapeutics to date. An important aspect of antibodies is their ability to bind antigen while at the same time recruit immune effector functions. The majority of approved recombinant monoclonal antibody therapies are of the...

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Bibliografiske detaljer
Principais autores: Xinhua Wang, Mary Mathieu, Randall J. Brezski
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2017-10-01
Serier:Protein & Cell
Fag:
Online adgang:http://link.springer.com/article/10.1007/s13238-017-0473-8
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