Disease association and comparative genomics of compositional bias in human proteins [version 2; peer review: 2 approved]

Background: The evolutionary rate of disordered protein regions varies greatly due to the lack of structural constraints. So far, few studies have investigated the presence/absence patterns of compositional bias, indicative of disorder, across phylogenies in conjunction with human disease. In this s...

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Detalhes bibliográficos

Principais autores:	Christos A. Ouzounis, Anastasia Chasapi, Christos E. Kouros, Vasiliki Makri
Formato:	Artigo
Idioma:	Inglês
Publicado em:	F1000 Research Ltd 2023-04-01
Colecção:	F1000Research
Assuntos:	disease-associated gene low complexity compositional bias intrinsically disordered protein (IDP) intrinsically disordered region (IDR) phylogenetic profile eng
Acesso em linha:	https://f1000research.com/articles/12-198/v2
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