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The Immunomodulatory Effects of Apigenin and Quercetin on Cytokine Secretion by the Human Gingival Fibroblast Cell Line and Their Potential Link to Alzheimer’s Disease

<b>Background:</b> The link between periodontal pathogens, inflammation, and neurodegenerative processes, including Alzheimer’s disease (AD), is evident. <i>Porphyromonas gingivalis</i> and <i>Treponema denticola</i> release lipopolysaccharide (LPS), constituting a virulence factor that takes part i...

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Principais autores: Anna Kurek-Górecka, Małgorzata Kłósek, Radosław Balwierz, Grażyna Pietsz, Zenon P. Czuba
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2025-04-01
Serier:Pharmaceuticals
Fag:
neurodegenerative disease
cytokines
apigenin
quercetin
periodontitis
Online adgang:https://www.mdpi.com/1424-8247/18/5/628
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