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L-DOPA increases slow-wave sleep duration and selectively modulates memory persistence in older adults

IntroductionMillions of people worldwide take medications such as L-DOPA that increase dopamine to treat Parkinson’s disease. Yet, we do not fully understand how L-DOPA affects sleep and memory. Our earlier research in Parkinson’s disease revealed that the timing of L-DOPA relative to sleep affects...

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Principais autores: Hanna K. Isotalus, Will J. Carr, Jonathan Blackman, George G. Averill, Oliver Radtke, James Selwood, Rachel Williams, Elizabeth Ford, Liz McCullagh, James McErlane, Cian O’Donnell, Claire Durant, Ullrich Bartsch, Matt W. Jones, Carlos Muñoz-Neira, Alfie R. Wearn, John P. Grogan, Elizabeth J. Coulthard
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2023-04-01
coleção:Frontiers in Behavioral Neuroscience
Assuntos:
sleep
memory
dopamine
ageing
slow wave sleep
NREM
Acesso em linha:https://www.frontiersin.org/articles/10.3389/fnbeh.2023.1096720/full
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