Efficient Oral Insulin Delivery Through Thiolated Trimethyl Chitosan-Grafted β-Cyclodextrin Nanoparticles

<b>Background</b>: Oral insulin improves compliance and convenience in patients with diabetes who require regular needle injections. However, the clinical application of oral insulin preparations has been limited due to instability and inefficient permeation through the gastrointestinal tract. In th...

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Autores principales:	Lizhen Yu, Fengge Wang, Shuyun Bao, Yue Zhang, Xuebin Shen, Desheng Wang, Zhisheng Liu, Xinyi Liu, Lihua Li, Renmin Gong
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	MDPI AG 2026-01-01
Colección:	Pharmaceutics
Materias:	oral drug delivery carrier insulin absorption barriers N-trimethyl chitosan thiolated polymer carboxymethyl-β-cyclodextrin
Acceso en línea:	https://www.mdpi.com/1999-4923/18/1/97
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