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Electroacupuncture alleviates comorbid obesity and depression via the gut-brain axis: orchestrating SCFA-producing bacteria and hippocampal synaptic plasticity

IntroductionComorbid obesity and depression (COMBD) represents a complex metabolic-neuropsychiatric challenge with limited therapeutic options. While Electroacupuncture (EA) is effective for both metabolic and mood disorders, the systemic mechanisms—particularly the interplay between the gut microbi...

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Principais autores: Yaxin Zhang, Yuxin Pang, Haoyuan Tan, Ronghui Xian, Junquan Liang, Qianyi Wen, Zhongxian Li, Luda Yan, Zeping Xie, Jingjing Li, Wenbin Fu, Peng Zhou
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2026-03-01
coleção:Frontiers in Microbiology
Assuntos:
depression
electroacupuncture
gut-brain axis
obesity
synaptic plasticity
Acesso em linha:https://www.frontiersin.org/articles/10.3389/fmicb.2026.1772788/full
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