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Signaling Lymphocyte Activation Molecule Family 5 Enhances Autophagy and Fine-Tunes Cytokine Response in Monocyte-Derived Dendritic Cells via Stabilization of Interferon Regulatory Factor 8

Signaling lymphocyte activation molecule family (SLAMF) receptors are essential regulators of innate and adaptive immune responses. The function of SLAMF5/CD84, a family member with almost ubiquitous expression within the hematopoietic lineage is poorly defined. In this article, we provide evidence...

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Principais autores: Zsofia Agod, Kitti Pazmandi, Dora Bencze, Gyorgy Vereb, Tamas Biro, Attila Szabo, Eva Rajnavolgyi, Attila Bacsi, Pablo Engel, Arpad Lanyi
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018-01-01
coleção:Frontiers in Immunology
Assuntos:
SLAMF5
autophagy
dendritic cell
IRF8
TRIM21
IL-12p70
Acesso em linha:http://journal.frontiersin.org/article/10.3389/fimmu.2018.00062/full
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