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Chromatin-mediated regulators of meiotic recombination revealed by proteomics of a recombination hotspot

Abstract Background Meiotic recombination hotspots control the frequency and distribution of Spo11 (Rec12)-initiated recombination in the genome. Recombination occurs within and is regulated in part by chromatin structure, but relatively few of the many chromatin remodeling factors and histone postt...

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Principais autores: Aaron J. Storey, Hsin-Ping Wang, Reine U. Protacio, Mari K. Davidson, Alan J. Tackett, Wayne P. Wahls
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2018-10-01
coleção:Epigenetics & Chromatin
Assuntos:
Homologous recombination
Meiosis
Histones
Chromatin remodeling
Mass spectrometry
Proteomics
Acesso em linha:http://link.springer.com/article/10.1186/s13072-018-0233-x
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